Method and bag set for concentrating white cells

Details Method and bag set for concentrating white cells Method and bag set for concentrating white cells

A - Human Necessities

61

K

A61K 35/14 (2006.01)

Patent

CA 2693293

A therapeutic product formed from a high concentration of white blood cells having a high degree of cell viability. The white blood cells are sequestered from their normal population presence in whole blood by placing the blood into a container and preventing coagulation of the blood, separating the blood into two components, one of which is extremely rich in white blood cells through the use of a reagent and centrifugation, sequestering the white cell concentration, and freezing the white cells. Specifically, the present invention relates to a therapeutic product comprising white blood cells in a solution having a constituent presence of at least one white cell part per one hundred red cells and a stem and progenitor cell viability of greater than 80%; and to a process by which the therapeutic process is formed.

L'invention porte sur un produit thérapeutique fabriqué à l'aide d'une grande concentration de leucocytes présentant un degré élevé de viabilité cellulaire. On isole les leucocytes à partir d'une population normale présente dans le sang entier en plaçant le sang dans un contenant, en empêchant la coagulation du sang, en séparant le sang en deux composantes, l'une étant extrêmement riche en leucocytes et étant obtenue par le recours à un réactif et une centrifugation, en isolant une concentration de leucocytes et en les congelant. Plus particulièrement, la présente invention porte sur un produit thérapeutique composé de leucocytes contenus dans une solution constituée d'au moins une partie de leucocytes par cent d'hématies et présentant une viabilité des cellules souches et des cellules progénitrices supérieure à 80 %, ainsi qu'un procédé par lequel le produit thérapeutique est formé.

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