Novel lapachone compounds and methods of use thereof

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 335/08 (2006.01) A61K 31/38 (2006.01) A61K 31/385 (2006.01) C07D 327/06 (2006.01) C07D 333/74 (2006.01)

Patent

CA 2506340

The invention provides lapachone analogs and derivatives as well as methods of use thereof. These compounds can be used in pharmaceutical compositions for the treatment or prevention of cell proliferation disorders. These compounds can also be used in the treatment or prevention of psoriasis or cancer or precancerous conditions.

L'invention concerne des analogues de lapachone et leurs dérivés ainsi que des procédés de fabrication. Ces composés peuvent s'utiliser dans des compositions pharmaceutiques pour le traitement ou la prévention des troubles de prolifération cellulaire. Lesdits composés peuvent également être utilisés dans le traitement ou la prévention du psoriasis ou du cancer ou d'états pathologiques précancéreux.

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