Method and apparatus for determining platelet function in...

Details Method and apparatus for determining platelet function in... Method and apparatus for determining platelet function in...

G - Physics

01

N

G01N 33/49 (2006.01) C12Q 1/56 (2006.01) G01N 33/483 (2006.01) G01N 33/86 (2006.01)

Patent

CA 2127899

A method for determining a platelet function in a primary hemostasis as provided in which a blood sample or a platelet containing fraction thereof is introduced into a vessel having a flat bottom which has an inner surface covered with a substrate capable of inducing platelet adhesion thereto and aggregation such as ECM (extracellular matrix). Preparation is then rotated inside the vessel, and consequently shear forces develop on the surface which bring to adhesion an aggregation of the blood platelets to the surface. Morphological parameters of blood aggregates are then determined.

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