C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/11 (2006.01) A61K 39/04 (2006.01) A61K 39/385 (2006.01) C07K 14/35 (2006.01) C07K 16/00 (2006.01) C07K 19/00 (2006.01) C12N 5/10 (2006.01)
Patent
CA 2378763
This invention relates to a polypeptide fragment which comprises an amino acid sequence encoded by a member of the esat-6 gene. A member of the esat-6 gene family is defined as gene encoding a small protein and that two such genes are arranged next to each other on the genome and that at least one of the gene products has an amino acid sequence identity to either Rv3874, Rv3875, or Rv0288 of at least 15 %.
L'invention concerne un fragment de polypeptide comprenant une séquence amicoacide codée par un membre génique esat-6. L'invention est caractérisée en ce qu'un membre de la famille génique esat-6 est défini comme gène codant pour une petite protéine, en ce que deux gènes de ce type sont disposés à proximité l'un de l'autre sur le génome, et en ce qu'au moins l'un des produits géniques présente une séquence aminoacide identifiée comme étant Rv3874, ou Rv3875, ou Rv0288, à raison d'au moins 15 %.
Andersen Peter
Skjot Rikke
Sim & Mcburney
Statens Serum Institut
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