C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/14 (2006.01) A61K 31/551 (2006.01) A61P 3/04 (2006.01) A61P 25/20 (2006.01) C07D 401/14 (2006.01) C07D 413/14 (2006.01) C07D 471/04 (2006.01) C07D 487/04 (2006.01) C07D 491/048 (2006.01) C07D 495/04 (2006.01)
Patent
CA 2670892
The present invention is directed to substituted diazepan compounds which are antagonists of orexin receptors, and which are useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which orexin receptors are involved.
La présente invention concerne des composés de diazépane substitués qui sont des antagonistes des récepteurs de l'orexine et se révèlent utiles pour le traitement ou la prévention de troubles et de maladies neurologiques et psychiatriques dans lesquels les récepteurs de l'orexine sont impliqués. L'invention concerne également des compositions pharmaceutiques renfermant ces composés ainsi que l'utilisation de ces composés et de ces compositions dans la prévention ou le traitement de maladies dans lesquelles les récepteurs de l'orexine sont impliqués.
Bergman Jeffrey M.
Breslin Michael J.
Coleman Paul J.
Cox Christopher D.
Mercer Swati P.
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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