Poxviral oncolytic vectors

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/86 (2006.01) A61K 35/76 (2006.01)

Patent

CA 2705873

The present invention relates to a poxvirus comprising a defective F2L gene, to composition comprising such poxvirus and to the methods and use of such compositions and poxviruses for therapeutic purposes, and more particularly for the treatment of cancer.

La présente invention porte sur un poxvirus comprenant un gène F2L défectueux, sur une composition comprenant un tel poxvirus et sur les procédés et l'utilisation de telles compositions et de tels poxvirus pour des objectifs thérapeutiques, et, plus particulièrement, pour le traitement du cancer.

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