C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 241/04 (2006.01) A61K 31/40 (2006.01) A61K 31/445 (2006.01) A61K 31/495 (2006.01) A61P 25/18 (2006.01) C07D 207/04 (2006.01) C07D 211/14 (2006.01) C07D 211/18 (2006.01) C07D 295/15 (2006.01) C07D 401/12 (2006.01) C07D 409/12 (2006.01)
Patent
CA 2707305
The present invention provides compounds that are glycine transporter 1 (hereinafter referred to as GlyT-1) in-hibitors and are therefore useful for the treatment of diseases treatable by inhibition of GlyT1 such as cognitive disorders associated with Schizophrenia, ADHD (attention deficit hyperactivity disorder), MCI (mild cognitive impairment), and the like. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds.
La présente invention propose des composés qui sont des inhibiteurs du transporteur de glycine 1 (ci-après appelé GlyT-1) et qui s'utilisent par conséquent dans le traitement de maladies pouvant être traitées par l'inhibition de GlyT1 telles que des troubles cognitifs associés à la schizophrénie, au trouble d'hyperactivité avec déficit de l'attention (ADHD), au trouble cognitif léger (MCI) et autres. L'invention propose également des compositions pharmaceutiques contenant de tels composés et des procédés de préparation de tels composés.
Amegadzie Albert
Hitchcock Stephen
Qian Wenyuan
Amgen Inc.
Gowling Lafleur Henderson Llp
LandOfFree
Glycine transporter-1 inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Glycine transporter-1 inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Glycine transporter-1 inhibitors will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1801448