Process for the preparation of 3,4-dihydroxybutanoic acid...

C - Chemistry – Metallurgy – 07 – C

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C07C 51/285 (2006.01) C07C 59/01 (2006.01) C07D 307/33 (2006.01) C07D 307/58 (2006.01)

Patent

CA 2049536

A process for the preparation of 3,4-dihydroxybutanoic acid (1) and salts thereof from a glucose source containing 1,4-linked glucose as a substituent is described. The process uses an alkali metal hdyroxide and hydrogen peroxide to convert the glucose source to (1). The compound (1) is useful as a chemical intermediate to naturally occurring fatty acids and is used to prepare 3,4-dihydroxybutanoic acid-gamma-lactone (2) and furanone (3), particularly stereoisomers of these compounds.

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