Glucagon-like peptide-1 crystals

Details Glucagon-like peptide-1 crystals Glucagon-like peptide-1 crystals

A - Human Necessities

61

K

A61K 38/26 (2006.01) C07K 14/605 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2315243

The invention provides individual tetragonal flat rod shaped or plate-like crystals of glucagon-like peptide-1 related molecules, processes for their preparation, compositions and methods of use. The crystal preparations exhibit extended time action in vivo and are useful for treating diabetes, obesity and related conditions.

L'invention concerne des cristaux isolés en forme de bâtonnet plat tétragonal ou en plaquettes de molécules apparentées au peptide 1 du type glucagon, des procédés de préparation, des compositions et des méthodes d'utilisation desdits cristaux. Ces préparations de cristaux ont une activité prolongée in vivo et conviennent pour le traitement du diabète, de l'obésité ou de pathologies associées.

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