Anti-tnf.alpha. antibodies in therapy of asthma

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/395 (2006.01) C07K 16/24 (2006.01)

Patent

CA 2364026

The present invention provides for uses of an anti-TNF.alpha. antibody or an antigen-binding fragment thereof for the manufacture of a medicament for use in the treatment of asthma or airway inflammation in an individual in need thereof. The present invention also provides for use of an anti-TNF.alpha. antibody or an antigen-binding fragment thereof for the manufacture of a medicament of use in reducing accumulation in lungs of inflammatory cells in an individual in need thereof.

La présente invention concerne des utilisations d'un anticorps anti-TNF.alpha. (facteur alpha nécrosant des tumeurs) ou d'un fragment de celui-ci se fixant sur un antigène, dans la fabrication d'un médicament utile dans le traitement de l'asthme ou de l'inflammation des voies aériennes, chez un individu nécessitant un tel traitement. L'invention concerne également l'utilisation d'un anticorps anti-TNF.alpha. ou d'un fragment de celui-ci se fixant sur un antigène, dans la fabrication d'un médicament utile pour réduire l'accumulation, dans les poumons, de cellules inflammatoires, chez un individu nécessitant un tel traitement.

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