Method for replicating the hepatitis c virus

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 7/00 (2006.01) C07K 14/18 (2006.01) C12P 21/02 (2006.01) G01N 33/576 (2006.01)

Patent

CA 2445596

The invention concerns the use of cells capable of carrying out a process of prenylation of proteins coded by the hepatitis C virus (HCV) genome, such as prenylation of the NS5A protein, for replicating and, if required, the production of HCV or derivative viable mutants, in a suitable culture medium.

L'invention concerne l'utilisation de cellules capables d'effectuer un processus de prénylation de proteines codées par le génome du virus de l'hépatite C (VHC), telle que la prénylation de la protéine NS5A, pour la réplication et, le cas échéant, la production du VHC ou de mutants viables dérivés, dans un milieu de culture approprié.

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