A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4035 (2006.01)
Patent
CA 2558607
Methods of treating, preventing and/or managing central nervous system disorders, such as Parkinson disease, Alzheimer disease, mild cognitive impairment, Huntington disease, Amytophic Lateral Sclerosis, depression and defective long-term memory, and related syndromes are disclosed. Specific methods encompass the administration of a selective cytokine inhibitory drug, or a pharmaceutically acceptable salt, solvate, hydrate, stereoisomer, clathrate, or prodrug thereof, alone or in combination with a second active ingredient. Pharmaceutical compositions, single unit dosage forms, and kits suitable for use in methods of the invention are also disclosed.
L'invention concerne des procédés de traitement, de prévention et/ou de gestion de troubles du système nerveux central, par exemple les maladies de Parkinson et d'Alzheimer, la déficience cognitive légère, la maladie de Huntington, la sclérose latérale amyotrophique, la dépression et la déficience de mémoire à long terme, et des syndromes connexes. L'invention concerne des procédés spécifiques consistant notamment à administrer un médicament sélectif inhibiteur de cytokine, ou un sel, un solvate, un hydrate, un stéréoisomère, un clathrate, ou un promédicament pharmaceutiquement acceptable de celui-ci, seul ou combiné à un second principe actif. Elle concerne également des compositions pharmaceutiques, des formes dosifiées unitaires, et des trousses appropriées pouvant être utilisées dans ces procédés.
Schafer Peter H.
Zeldis Jerome B.
Celgene Corporation
Smart & Biggar
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