Use of flavone 8-acetic acid in vascular and cardiovascular...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/352 (2006.01) A61K 45/06 (2006.01) A61P 9/00 (2006.01) A61K 31/35 (2006.01)

Patent

CA 2389924

A method for treatment of a vascular or cardiovascular condition or acute coronary syndromes comprises administering an effective amount of a flavone 8- carboxylic acid to a mammal suffering from a vascular or cardiovascular condition or acute coronary syndromes. The flavone 8-carboxylic acid is typically flavone 8-acetic acid. The flavone 8-carboxylic acid can be administered alone or in combination with another agent such as a thrombolytic agent, an antithrombotic agent, an anticoagulant, or an antiplatelet agent. The invention also includes pharmaceutical compositions formulated for the treatment of a vascular or cardiovascular condition or acute coronary syndromes.

L'invention concerne une méthode destinée au traitement d'un état pathologique vasculaire ou cardiovasculaire ou de syndromes coronariens aigus. Cette méthode consiste à administrer une dose efficace d'un acide 8-carboxylique de flavone à un mammifère présentant un état pathologique vasculaire ou cardiovasculaire ou des syndromes coronariens aigus. Cet acide 8-carboxylique de flavone se présente généralement sous la forme d'un acide 8-acétique de flavone. Ledit acide 8-carboxylique de flavone peut être administré isolément ou en combinaison avec un autre agent, tel qu'un agent thrombolytique, un agent antithrombotique, un anticoagulant ou un agent antiplaquettaire. L'invention concerne également des compositions pharmaceutiques destinées au traitement d'un état pathologique vasculaire ou cardiovasculaire ou de syndromes coronariens aigus.

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