A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/20 (2006.01) A61K 31/40 (2006.01)
Patent
CA 2691956
The present invention relates to the formulation of solid dosage forms comprising a therapeutically effective amount of an HMG-CoA reductase inhibitor, and especially Atorvastatin or Fluvastatin or salts thereof, in combination with colloidal clay such as Attapulgite, and a process for the preparation thereof by direct compression.
La présente invention concerne la formulation de formes posologiques solides comprenant une quantité efficace sur le plan thérapeutique d'un inhibiteur de la HMG-CoA réductase, et particulièrement l'atorvastatine ou la fluvastatine ou leurs sels, en combinaison avec une argile colloïdale telle que l'attapulgite, et un procédé pour leur préparation par compression directe.
Bikiaris Dimitrios
Ioannidou Elli
Karavas Evangelos
Koutris Efthimios
Samara Vicky
Dimock Stratton Llp
Pharmathen S.a.
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