Peptides and vaccines derived from nematode tubulin

Details Peptides and vaccines derived from nematode tubulin Peptides and vaccines derived from nematode tubulin

A - Human Necessities

61

K

A61K 39/00 (2006.01) C07K 14/435 (2006.01) C07K 16/18 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2147756

The present invention relates to a monoclonal antibody which substantially binds to .beta.-tubulin of nematode origin and frag- ments thereof. There is provided a hybridoma cell line producing the monoclonal antibody of the present invention which has been deposited at the ATCC under the accession number HB 11129. The antibody of the present invention can be used as an anti- parasitic agent and a diagnostic agent for parasitic diseases. The present invention also relates to the use of an antigen, which is recognized by the monoclonal antibody, as an immunizing agent and in vaccine compositions.

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