Isolated human tumor supressor proteins, nucleic acid...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 45/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12P 21/02 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2439155

The present invention provides amino acid sequences of polypeptides that are encoded by genes within the human genome, the tumor supressor protein polypeptides of the present invention. The present invention specifically provides isolated polypeptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the tumor supressor protein polypeptides, and methods of identifying modulators of the tumor supressor protein polypeptides.

L'invention concerne des séquences d'acides aminés de polypeptides codées par des gènes dans le génome humain, les polypeptides de protéines suppresseurs de tumeur selon l'invention. L'invention concerne en particulier des molécules isolées de polypeptides et d'acides nucléiques, des procédés d'identification d'orthologues et de paralogues des polypeptides de protéines suppresseurs de tumeur, ainsi que des procédés d'identification de modulateurs des polypeptides de protéines suppresseurs de tumeur.

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