Sub-type selective amides of diazabicycloalkanes

Details Sub-type selective amides of diazabicycloalkanes Sub-type selective amides of diazabicycloalkanes

C - Chemistry, Metallurgy

07

D

C07D 471/08 (2006.01) A61K 31/407 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2716863

The present invention relates to compounds of the following formula (I) that bind to and modulate the activity of neuronal nicotinic acetylcholine receptors, to processes for preparing these compounds, to pharmaceutical compositions contain-ing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders, including those associated with dysfunction of the central nervous system (CNS).

La présente invention concerne des composés de la formule (I) suivante qui se lient à des récepteurs d'acétylcholine nicotinique neuronaux et modulent l'activité de ceux-ci, des procédés pour préparer ces composés, des compositions pharmaceutiques contenant ces composés, et des procédés d'utilisation de ces composés pour traiter une grande diversité d'états et de troubles, y compris ceux associés à un dysfonctionnement du système nerveux central (CNS).

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