Tumor-associated antigen

Details Tumor-associated antigen Tumor-associated antigen

C - Chemistry, Metallurgy

07

K

167/139, 167/37,

C07K 16/30 (2006.01) A61K 39/395 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C12N 5/12 (2006.01) C12P 21/08 (2006.01) G01N 33/574 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2028024

H-7610 ABSTRACT A novel tumor-associated antigen expressed by lung adenocarcinoma is disclosed. The antigen, characterized by its reactivity to monoclonal antibody LA20207, has a molecular weight in the range of about 50,000 to about 80,000 daltons and an isoelectric point in the range of about 4.9 to about 6.5. Antibodies directed against the antigen, methods for their production and diagnostic and therapeutic uses therefor are also provided.

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