Pluripotent cells comprising allogenic nucleus and mitochondria

Details Pluripotent cells comprising allogenic nucleus and mitochondria Pluripotent cells comprising allogenic nucleus and mitochondria

C - Chemistry, Metallurgy

12

N

C12N 5/00 (2006.01) A01K 67/027 (2006.01) C12N 5/02 (2006.01) C12N 5/16 (2006.01) C12N 5/26 (2006.01) C12N 15/00 (2006.01) C12N 15/87 (2006.01) A61K 35/12 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01)

Patent

CA 2405555

Allochimeric ES cells are provided having nuclei from one individual of a species and mitochondria from a different individual of the same species. The ES cells can be used for differentiation into differentiated cell types for therapy or for studying various developmental processes in forming embryos and differentiation.

La présente invention concerne des cellules souches embryonnaires (ES) allochimériques dont les noyaux proviennent d'un individu d'une espèce et les mitochondries proviennent d'un individu différent de la même espèce. Les cellules ES peuvent être utilisées pour effectuer la différenciation en types de cellules différenciées à des fins thérapeutiques ou de recherche portant sur les divers processus de développement impliqués dans la formation des embryons et la différenciation.

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