Stabilisation of pharmacologically active compounds in...

Details Stabilisation of pharmacologically active compounds in... Stabilisation of pharmacologically active compounds in...

C - Chemistry, Metallurgy

07

K

C07K 14/695 (2006.01) A61K 9/16 (2006.01) A61K 38/09 (2006.01) A61K 38/16 (2006.01) A61K 38/35 (2006.01) A61K 39/08 (2006.01) A61K 47/12 (2006.01) A61K 47/22 (2006.01) C07K 7/23 (2006.01)

Patent

CA 2123144

Abstract A pharmaceutical composition comprises as the active agent a peptide in association with embonic acid or ascorbic acid or a salt thereof, excluding 1) ACTH in association with embonic acid or ascorbic acid or a salt thereof and 2) a LHRH active compound in association with ascorbic acid or a salt thereof, in a matrix of a polylactide, having a lactide/glycolide molar ratio of from 100:0 to 40:60, a Mw of from 10.000 to 200.000 and a polydispersity of from 1.7 to 3Ø It is used for sustained release.

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