A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/14 (2006.01) A61K 9/20 (2006.01) A61K 9/46 (2006.01) A61K 9/48 (2006.01) A61K 47/02 (2006.01) A61K 47/12 (2006.01)
Patent
CA 2436570
A novel method is provided for enhancing dispersion of drug-containing particles in an aqueous medium. According to this method, a solid dosage form of the drug is provided having incorporated therein a dispersion-enhancing amount of an effervescent agent wherein (a) the dosage form is adapted for swallowing without prior disintegration in water or in the mouth, and (b) the amount of the effervescent agent is not sufficient to substantially enhance disintegration of the dosage form in the aqueous medium.
L'invention concerne un nouveau procédé permettant d'améliorer la dispersion de particules contenant un médicament dans un support aqueux. Selon ce procédé, une forme posologique solide du médicament possède en elle une quantité d'un agent effervescent renforçant la dispersion dans lequel (a) la forme posologique est adaptée pour être avalée sans désintégration préalable dans l'eau ou dans la bouche et où (b) la quantité d'agent effervescent ne suffit pas à renforcer, de manière significative, la désintégration de la forme posologique dans le support aqueux.
Pharmacia Corporation
Smart & Biggar
LandOfFree
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