Composition for sealing wounds

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/36 (2006.01) A61K 9/70 (2006.01) A61K 38/48 (2006.01) A61L 15/32 (2006.01) A61L 24/10 (2006.01)

Patent

CA 2245585

A hemostatic bandage contains powdered fibrinogen and thrombin adhered to a fibrous matrix with a viscous, nonaqueous adhesive such as a viscous polysaccharide, glycol, or petroleum jelly. The nonaqueous adhesive does not allow a hydrolytic reaction to occur between the fibrinogen and thrombin until the bandage is moistened by a body fluid, such as blood. Hence the bandage can be prepared and stored for prolonged periods while retaining hemostatic activity.

Un pansement hémostatique comprend du fibrinogène et de la thrombine en poudre adhérant à une matrice fibreuse par un adhésif visqueux non aqueux tel qu'un polysaccharide visqueux, un glycol ou du pétrolatum. L'adhésif non aqueux ne permet pas la réaction hydrolytique entre le fibinogène et la thrombine avant que le pansement ne soit humecté par un fluide du corps, par exemple le sang. Dans ces conditions, le pansement peut être préparé et conservé pendant un longue durée, sans perdre ses qualités hémostatiques.

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