Sulfonylamino-substituted benzoylguanidines, a process for...

C - Chemistry – Metallurgy – 07 – C

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C07C 311/08 (2006.01) A61K 31/18 (2006.01) A61K 31/275 (2006.01) A61K 31/33 (2006.01) A61K 49/00 (2006.01) C07C 307/10 (2006.01) C07C 311/48 (2006.01) C07C 323/44 (2006.01) C07D 207/36 (2006.01) C07D 213/62 (2006.01) C07D 213/65 (2006.01) C07D 215/20 (2006.01) C07D 233/70 (2006.01) C07D 307/58 (2006.01) C07D 333/32 (2006.01)

Patent

CA 2190220

Sulfonylamino-substituted benzoylguanidines, a process for their preparation, their use as medicament or diagnostic aid, and medicament containing them Benzoylguanidines of the formula ? Image ? in which R(1) to R(6) have the meanings stated in the claims, are antiarrhythmic pharmaceuticals which have excellent activity and a cardioprotective component and are highly suitable for the prophylaxis of infarcts and the treatment of infarcts, and for the treatment of angina pectoris, in which case they also preventively inhibit or greatly reduce the pathophysiological processes in the development of ischemia-induced damage, especially in the triggering of ischemia-induced cardiac arrhythmias.

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