Rev-independent hiv expression and replication

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/867 (2006.01) C07H 21/00 (2006.01) C12N 7/01 (2006.01) C12N 15/10 (2006.01) C12N 15/11 (2006.01) C12P 19/34 (2006.01) C12Q 1/68 (2006.01) C12Q 1/70 (2006.01)

Patent

CA 2142746

Methods and compositions, involving a novel nucleotide sequence termed a "constitutive transport enhancer", are provided for expression of heterologous genes whose mRNA is either differentially spliced, alternatively spliced, incompletely spliced, or unspliced; for a rev-independent HIV expression system; and for rev-independent HIV replication.

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