Use of certain isoquinolinesulfonyl compounds for the...

A - Human Necessities – 61 – K

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A61K 31/551 (2006.01) A61K 9/00 (2006.01) A61K 31/47 (2006.01) A61P 27/06 (2006.01)

Patent

CA 2240271

Isoquinolinesulfonyl compounds are used in ophthalmic compositions to treat glaucoma or other ischemic-borne ocular disorders such as retinopathles or optic neuropathies. These compounds vasodilate ocular blood vessels, lower IOP and prevent or reduce the progression of visual field loss.

Cette invention concerne des composés d'isoquinolinesulfonyle, lesquels sont utilisés dans des compositions ophtalmiques afin de traiter des glaucomes ou d'autres troubles oculaires d'origine ischémique, tel que des rétinopathies ou des neuropathies optiques. Ces composés permettent d'effectuer une vasodilatation des vaisseaux sanguins oculaires, d'abaisser la pression intra-oculaire, et de prévenir ou réduire la progression d'une perte du champ visuel.

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