A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/08 (2006.01) A61K 38/04 (2006.01) A61K 49/00 (2006.01) A61K 51/04 (2006.01)
Patent
CA 2187459
The permeability of the blood-ocular barrier to therapeutic or diagnostic agents in the bloodstream of a host is increased by administering a permeabilizer peptide, preferably bradykinin or a bradykinin analogue, into the bloodstream of a host. The invention provides methods of treatment or diagnosis of ocular diseases by administration of a permeabilizer peptide, such as permeabilizer A-7, in combination with a therapeutic or diagnostic agent.
L'invention porte sur un moyen d'accroître la perméabilité de la barrière hémato-oculaire vis-à-vis d'agents thérapeutiques ou diagnostiques par injection dans la circulation sanguine du patient d'un peptide de perméabilisation, de préférence de la bradykinine ou l'un de ses analogues; elle porte également sur des méthodes de traitement ou de diagnostic de troubles oculaires par administration de peptides de perméabilisation tels que l'A-7, associés à un agent thérapeutique ou diagnostique.
Alkermes Controlled Therapeutics Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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