A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/00 (2006.01) A61K 9/06 (2006.01) A61K 31/445 (2006.01)
Patent
CA 2709538
The present invention relates to pharmaceutical formulation containing tolperisone or its pharmaceutically acceptable salts or tolperisone combined with a non-steroidal anti-inflammatory drug or their salts, gel forming macromolecule, solvent, and if required thickening agent, penetration enhancer and pH adjuvant or the mixture thereof. The invention also relates to the manufacturing process of the above mentioned pharmaceutical compositions, further the use of these formulations and the containers suitable for the dosage, which are dual compartment containers consisting of two separated chambers.
L'invention concerne une formulation pharmaceutique contenant tolperisone ou ses sels acceptables sur le plan pharmaceutique ou tolperisone combiné à un médicament anti-inflammatoire non stéroïde ou leurs sels, une macromolécule formant un gel, un solvant et, si nécessaire, un agent épaississant, un activateur de pénétration, ainsi qu'un adjuvant de pH ou leur mélange. Elle concerne également le procédé de préparation de ces compositions pharmaceutiques, l'utilisation de ces formulations et les récipients adéquats pour leur dosage, qui consistent en des récipients à double compartiment constitués de deux chambres séparées.
Balazs Ottilia
Hornok Katalin
Kis-Varga Istvanne
Tihanyi Karoly
Viragh-Hadas Maria
G. Ronald Bell & Associates
Richter Gedeon Nyrt.
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