Use of peo-pbo block copolymers in ophthalmic compositions

Details Use of peo-pbo block copolymers in ophthalmic compositions Use of peo-pbo block copolymers in ophthalmic compositions

C - Chemistry, Metallurgy

11

D

C11D 3/00 (2006.01) C11D 1/00 (2006.01) C11D 3/37 (2006.01)

Patent

CA 2671376

The use of poly(oxyethylene)-poly(oxybutylene) block copolymers in pharmaceutical compositions useful for modifying the surfaces of contact lenses and other medical devices is disclosed. The present invention is based in-part on a discovery that this class of compounds is particularly efficient in wetting hydrophobic surfaces, such as the surfaces of silicone hydrogel contact lenses and other types of ophthalmic lenses. Such compounds are also useful for cleaning purposes. The use of the compounds as surfactants in various types of compositions for treating contact lenses therefore represents a preferred embodiment of the present invention.

L'invention concerne l'utilisation de copolymères séquencés de poly(oxyéthylène)-poly(oxybutylène) dans des compositions pharmaceutiques utiles pour modifier les surfaces de lentilles de contact et d'autres dispositifs médicaux. La présente invention repose en partie sur la découverte que cette catégorie de composés est particulièrement efficace dans le mouillage de surfaces hydrophobes, telles que les surfaces de lentilles de contact, en hydrogel de silicone et d'autres types de lentilles ophtalmiques. De tels composés sont également utiles à des fins de nettoyage. L'utilisation des composés comme agents tensioactifs dans divers types de compositions de traitement de lentilles de contact constitue, par conséquent, un mode de réalisation préféré de la présente invention.

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