Mixtures of caspase inhibitors and complement inhibitors and...

A - Human Necessities – 61 – K

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A61K 45/06 (2006.01) A61K 31/198 (2006.01) A61K 35/12 (2006.01) A61K 35/58 (2006.01) A61K 38/07 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61P 37/06 (2006.01) C07K 16/18 (2006.01)

Patent

CA 2399969

Combinations of caspase inhibitors and complement inhibitors are described. Methods for preventing and/or treating transplant rejection, and in particular rejection of xenotransplants, involving treating the graft material and/or the transplant recipient with a combination of a caspase inhibitor and a complement inhibitor are also described.

L'invention concerne des combinaisons d'inhibiteurs de caspase et d'inhibiteurs de complément. L'invention concerne également des méthodes de prévention et/ou de traitement de rejet de greffe, et en particulier du rejet de xénogreffes, consistant à traiter la matière greffée et/ou le receveur de greffe avec une combinaison d'un inhibiteur de caspase et d'un inhibiteur de complément.

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