Cell proliferation assay

Details Cell proliferation assay Cell proliferation assay

C - Chemistry, Metallurgy

12

Q

C12Q 1/00 (2006.01) C12Q 1/66 (2006.01)

Patent

CA 2406873

Disclosed are compositions and methods useful for measuring cell proliferation. The methods use a luciferase polypeptide to assess changes in cell number. Also disclosed are methods to diagnose and monitor cell proliferative disorders including cancer. In addition, the methods disclosed are useful for identifying agents that modulate cell proliferation.

Cette invention se rapporte à des compositions et à des procédés servant à mesurer la prolifération de cellules. Ces procédés utilisent un polypeptide de luciférase pour évaluer des variations du nombre des cellules. Cette invention concerne également un procédé pour diagnostiquer et suivre les affections prolifératives cellulaires. Les procédés faisant l'objet de cette invention servent à identifier des agents permettant de moduler la prolifération de cellules.

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