Pharmaceutical compositions of arglabin and arglabin...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/365 (2006.01) A61K 31/28 (2006.01) A61K 31/335 (2006.01) A61K 31/34 (2006.01) A61K 31/343 (2006.01) A61K 31/35 (2006.01) A61K 31/475 (2006.01) A61K 31/505 (2006.01) A61K 31/5377 (2006.01) A61K 31/56 (2006.01) A61K 31/675 (2006.01) A61K 31/70 (2006.01) A61K 33/24 (2006.01) A61K 45/06 (2006.01) C07D 307/93 (2006.01) C07D 493/04 (2006.01) C07D 493/10 (2006.01) C07D 493/20 (2006.01)

Patent

CA 2287318

Pharmaceutical compositions containing arglabin and arglabin derivatives are described. The compositions can be in unit dosage form and are useful for the treatment of cancer in humans. Compositions and kits containing a first chemotherapeutic agent that includes arglabin or a derivative thereof and a second chemotherapeutic agent are also described. The compositions and kits are effective for treating cancer in a human patient. The invention also provides various derivatives of arglabin, effective for suppressing tumor growth in mammals.

L'invention concerne des compositions pharmaceutiques contenant de l'arglabine et des dérivés d'arglabine. Lesdites compositions peuvent se présenter sous forme de dose unitaire et sont utiles pour le traitement du cancer chez les humains. L'invention porte aussi sur des kits contenant un premier agent contenant de l'arglabine ou un dérivé de celle-ci et un deuxième agent chimiothérapeutique. Les compositions et les kits sont efficaces pour le traitement du cancer chez un patient humain. L'invention porte encore sur divers dérivés de l'arglabine, efficaces pour la suppression de la croissance tumorale chez les mammifères.

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