Microfluidized leishmania antigen and methods of making and...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/44 (2006.01) A61K 39/008 (2006.01) A61K 49/00 (2006.01) C07K 16/20 (2006.01) C12N 1/06 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2463581

Disclosed herein are microfluidized lysate preparations of Leishmania parasites and methods of making thereof. Also disclosed are methods of using the microfludized lysate preparations in skin test antigen assays as well as kits comprising the microfluidized lysate preparations. The microfluidized lysate preparations are made under current good manufacturing practice and may therefore be standarized and such preparations may be produced with consistently.

La présente invention concerne des préparations de lysat microfluidisé de parasites leishmania et des techniques de fabrication de celles-ci. Cette invention concerne aussi des techniques d'utilisation de ces préparations de lysat microfluidisé dans des dosages d'antigène de test cutané ainsi que des kits comprenant ces préparations de lysat microfluidisé. Ces préparations de lysat microfluidisé sont fabriquées selon de bonnes pratiques de fabrication courantes et peuvent donc être normalisées. Ces préparations peuvent être produites de façon uniforme.

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