Ophthalmic compositions containing loratadine

Details Ophthalmic compositions containing loratadine Ophthalmic compositions containing loratadine

A - Human Necessities

61

K

A61K 31/445 (2006.01) A61K 9/00 (2006.01) A61K 31/4545 (2006.01)

Patent

CA 2512251

The present invention is directed to an ophthalmic formulation which comprises a therapeutically effective amount of ethyl 4-(8-chloro-5,6-dihydro-11- benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylate, known as loratadine, a fatty acid ester, and a surfactant, which has been found to be useful in treating ocular allergies, especially allergic conjunctivitis, and related conditions.

L'invention concerne une formulation ophtalmique contenant une quantité thérapeutiquement efficace de carboxylate d'éthyl 4-(8-chloro-5,6-dihydro-11-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidène)-1-piperidine, connu sous le nom de loratadine, un ester d'acides gras, et un tensioactif, qui s'est avérée être utile dans le traitement des allergies oculaires, en particulier de la conjonctivite allergique, et d'états pathologiques apparentés.

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