Osmotic dosage form comprising first and second coats

Details Osmotic dosage form comprising first and second coats Osmotic dosage form comprising first and second coats

A - Human Necessities

61

K

A61K 9/24 (2006.01) A61K 9/00 (2006.01)

Patent

CA 2389568

A dosage form is described having a drug core, an inner, fluid-permeable membrane surrounding the drug core, and an outer, semipermeable membrane having exit means formed or formable therein surrounding the inner membrane. The drug core forms a solution with imbibed fluid through the membranes and dissolves the inner membrane over time, thereby furthering the maintenance of controlled, sustained delivery of drug from the dosage form.

Cette invention concerne une forme posologique comprenant un noyau de médicament, une membrane intérieure perméable aux liquides et une membrane extérieure semi-perméable comportant un dispositif de sortie formé ou pouvant être formé sur ladite membrane, autour de la membrane intérieure. Le noyau de médicament forme une solution avec un liquide imprégnant les membranes et dissout à la longue la membrane intérieure, ce qui favorise l'administration régulée et soutenue du médicament à partir de la forme posologique.

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