Methods and compositions for identifying therapeutic compounds

Details Methods and compositions for identifying therapeutic compounds Methods and compositions for identifying therapeutic compounds

C - Chemistry, Metallurgy

12

Q

C12Q 1/44 (2006.01)

Patent

CA 2543294

By the present invention, enzymes responsible for prodrug activation are identified and utilized for the identification of candidate compounds as prodrugs. The present invention includes methods for identifying a candidate compound as a suitable prodrug as well as methods of screening candidate compounds for suitability as therapeutic agents.

L'invention concerne des enzymes responsables de l'activation de promédicaments, identifié et utilisé pour l'identification de composés candidats comme promédicaments. L'invention concerne également des procédés pour l'identification d'un composé candidat comme un promédicament approprié ainsi que des procédés de criblage de composés candidats en tant qu'agents thérapeutiques.

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