Process for the purification of antithrombin-iii

Details Process for the purification of antithrombin-iii Process for the purification of antithrombin-iii

C - Chemistry, Metallurgy

07

K

C07K 1/22 (2006.01) C07K 14/81 (2006.01)

Patent

CA 2395594

The present invention relates to a process for the preparation of a solution comprising a substantially pure isoform of AT-III, said process comprising separating the isoform AT-III.alpha. from AT-III.beta. on a calcium hydroxyphosphate-based adsorbent.

L'invention concerne un procédé permettant de préparer une solution comprenant un isoforme sensiblement pur de AT-III. Ce procédé consiste à séparer l'isoforme AT-III.alpha. de l'isoforme AT-III.beta. sur un adsorbant à base d'hydroxyphosphate de calcium.

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