Method of treating chronic ulcers

Details Method of treating chronic ulcers Method of treating chronic ulcers

A - Human Necessities

61

K

A61K 35/12 (2006.01) A61K 31/715 (2006.01) A61K 35/74 (2006.01) A61K 38/01 (2006.01) A61K 38/39 (2006.01) A61L 26/00 (2006.01) A61L 27/52 (2006.01) A61P 17/02 (2006.01) A61Q 7/00 (2006.01)

Patent

CA 2410968

The invention provides a method of treating a chronic ulcer, such as a diabetic ulcer, comprising administering a therapeutic amount of a hydrogen matrix to the ulcer, the matrix composition comprising gelatin and a long chain carbohydrate. The matrix may further include polar amino acids, nitric oxide inhibitors and super oxide inhibitors. Injection is a preferred method of administration. The matrix may be injected into one or more locations within the ulcer, underneath the ulcer and/or around the periphery of the ulcer.

L'invention concerne une méthode permettant de traiter un ulcère chronique, tel qu'un ulcère diabétique, consistant à administrer une quantité thérapeutique d'une matrice d'hydrogel dans l'ulcère. La composition de cette matrice comprend de la gélatine et un glucide à chaîne longue. Cette matrice peut en outre contenir des acides aminés polaires, des inhibiteurs d'oxyde nitrique, et des inhibiteurs de superoxydes. Le mode d'administration préféré est l'administration par injection. La matrice peut être injectée dans un ou plusieurs emplacements situés dans l'ulcère, sous l'ulcère et/ou sur le pourtour de l'ulcère.

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