A nitroimidazole gel composition

A - Human Necessities – 61 – K

Patent

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Details

A61K 47/38 (2006.01) A61K 31/4164 (2006.01) A61K 47/00 (2006.01) A61K 47/10 (2006.01) A61K 47/02 (2006.01) A61K 47/12 (2006.01)

Patent

CA 2275429

A viscous hydrogel composition, for use in a topical treatment of a skin condition involving dry or inflammed skin, comprising an antimicrobially active nitroimidazole drug, a water miscible alkylene glycol, a hydroxyalkyl cellulose gelling agent and water, buffered to have a physiologically acceptable pH and a method of making the same.

L'invention concerne une composition visqueuse d'hydrogel, destinée à être utilisée dans un traitement topique d'une affection de la peau impliquant une peau sèche ou enflammée, qui comprend un médicament antimicrobien à base de nitro-imidazole, un glycol d'alkylène miscible avec l'eau, un agent gélifiant cellulosique hydroxyalkylé et de l'eau, et qu'on tamponne pour lui donner un pH physiologiquement acceptable. L'invention concerne également son procédé de fabrication.

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