Use of targeted oxidative therapeutic formulation in bone...

A - Human Necessities – 61 – K

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A61K 47/10 (2006.01) A61K 47/18 (2006.01) A61K 47/22 (2006.01)

Patent

CA 2566188

A pharmaceutical formulation and its use. The pharmaceutical formulation contains peroxidic species or reaction products resulting from oxidation of an alkene, such as geraniol, by an oxygen-containing oxidizing agent, such as ozone; a penetrating solvent, such as dimethylsulfoxide (~DMSO~); a dye containing a chelated metal, such as hematoporphyrin; and an aromatic redox compound, such as benzoquinone. The pharmaceutical formulation is used to effectively stimulate bone regeneration and increase osteoblastic activity in a patient.

L'invention concerne une formulation pharmaceutique et son utilisation. La formulation pharmaceutique contient une espèce peroxydique ou des produits de réaction résultant de l'oxydation d'un alcène, tel que le géraniol, par un agent d'oxydation oxygéné, tel que l'ozone; un solvant de pénétration, tel que le diméthylsulfoxyde (DMSO); un colorant contenant un métal chélaté, tel que l'hématoporphyrine; et un composé redox aromatique, tel que la benzoquinone. Cette formulation pharmaceutique est utilisée pour stimuler efficacement la régénération osseuse et augmenter l'activité ostéoblastique chez un patient.

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