Certain cycloalkyl and azacycloalkyl pyrrolopyrimidines; a...

Details Certain cycloalkyl and azacycloalkyl pyrrolopyrimidines; a... Certain cycloalkyl and azacycloalkyl pyrrolopyrimidines; a...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) C07D 471/14 (2006.01) C07D 487/20 (2006.01) C07D 491/12 (2006.01) C07D 491/20 (2006.01)

Patent

CA 2091986

This invention encompasses compounds of the formula: Image and pharmaceutically acceptable non-toxic salts thereof wherein: n is 0, 1 or 2, and R1, R2, X, Y and W are variables. These compounds are highly selective agonists, antagonists or inverse agonists for GABAa brain receptors or prodrugs thereof and are useful in the diagnosis and treatment of anxiety, sleep, and seizure disorders, overdose with benzodiazepine type drugs, and enhancement of alertness.

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