Non-sedating barbituric acid derivatives

Details Non-sedating barbituric acid derivatives Non-sedating barbituric acid derivatives

A - Human Necessities

61

K

A61K 31/515 (2006.01) A61K 31/675 (2006.01)

Patent

CA 2471436

The present invention relates to novel non-sedating barbituric acid derivatives, pharmaceutical compositions containing them and methods of neuroprotection in cases of cerebral ischemia, head trauma and other acute neurologic injuries, and prevention of resulting neuronal damage. The invention also relates to the use of non-sedating barbituric acid derivatives given in a manner and dosage effective to produce blood levels and brain levels of these drugs and/or their active metabolites sufficient to provide a therapeutic effect.

L'invention se rapporte à des nouveaux dérivés d'acide barbiturique non sédatifs, à des compositions pharmaceutiques contenant ces dérivés et à des procédés de neuroprotection dans des cas d'ischémie cérébrale, de traumatisme crânien et d'autres troubles neurologiques aigus, ainsi qu'à des procédés de prévention des lésions neuronales qui en résultent. L'invention se rapporte également à l'utilisation de dérivés d'acide barbiturique non sédatifs administrés à une dose efficace pour produire des concentrations sanguines et des concentrations cérébrales de ces médicaments et/ou de leurs métabolites actifs suffisantes pour obtenir un effet thérapeutique.

Affiliated with

Also associated with

Rating

Non-sedating barbituric acid derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Non-sedating barbituric acid derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Non-sedating barbituric acid derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1816959