C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
C07F 15/00 (2006.01) A61K 9/127 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) A61K 51/06 (2006.01) C07C 235/12 (2006.01) C07C 271/20 (2006.01) C07F 1/08 (2006.01) C07F 5/02 (2006.01) C07F 15/06 (2006.01) C08J 9/00 (2006.01)
Patent
CA 2171218
Unimolecular micelles, generally referred to as cascade polymers, are constructed via the addition of successive layers, or tiers, of designed monomers, or building blocks, that possess a predetermined, branched superstructure consisting of connected physical matter inherently defining an internal void volume or void area within the molecular framework. Each of the branches define a flexible arm from a central core atom and terminate with a hydrodynamic reactive group. A method is described for manipulating such cascade polymers.
On construit des micelles unimoléculaires, généralement appelées polymères en cascade, en ajoutant des couches successives, ou gradins, de monomères spécifiques, ou encore des blocs structuraux, qui possèdent une superstructure ramifiée prédéterminée constituée de matière physique connectée qui définit de manière inhérente un volume de vide interne ou une zone de vide dans le squelette moléculaire. Chaque ramification définit un bras souple qui part d'un atome de noyau central et se termine par un groupe réactif hydrodynamique. Un procédé de manipulation de ces polymères en cascade est également décrit.
Moorefield Charles N.
Newkome George R.
Borden Ladner Gervais Llp
University Of South Florida
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