Alphavirus replicon packaging constructs

Details Alphavirus replicon packaging constructs Alphavirus replicon packaging constructs

C - Chemistry, Metallurgy

12

N

C12N 15/86 (2006.01) A61K 48/00 (2006.01) C12N 5/10 (2006.01) C12N 7/00 (2006.01)

Patent

CA 2567047

Provided herein are modified, functional 5' amplification sequences that are defective packaging signals. Also provided are compositions and methods comprising these modified 5' amplification sequences.

L'invention concerne des séquences d'amplification fonctionnelles (5') modifiées constituées par des signaux d'encapsidation défaillante. L'invention concerne des compositions et des méthodes comprenant ces séquences d'amplification (5') modifiées.

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