Compositions and methods utilizing dna polymerases

Details Compositions and methods utilizing dna polymerases Compositions and methods utilizing dna polymerases

C - Chemistry, Metallurgy

12

N

C12N 9/12 (2006.01) C12P 19/34 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2451677

The invention features a novel isolated Family B DNA polymerase, a Thermococcus polymerase JDF-3, and mutant recombinant forms thereof. Mutant polymerases of the invention are deficient in 3~ to 5~ exonuclease activity and/or exhibit reduced discrimination against non-conventional nucleotides relative to the wild-type form of the polymerase.

La présente invention concerne une polymérase d'ADN isolée appartenant à la famille B, en l'occurrence une polymérase JDF-3 de Thermococcus, et certaines formes recombinantes mutantes. Les polymérases mutantes de l'invention présentent un déficit d'activité des exonucléases 3' à 5' et/ou font preuve, contre les nucléotides non conventionnels, d'une discrimination inférieure à celle de la forme de type sauvage de la polymérase.

Affiliated with

Also associated with

Rating

Compositions and methods utilizing dna polymerases does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Compositions and methods utilizing dna polymerases, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compositions and methods utilizing dna polymerases will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1818832