Piperazine derivatives and their use as 5-ht1a antagonists

C - Chemistry – Metallurgy – 07 – D

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C07D 405/12 (2006.01) A61K 31/495 (2006.01) C07D 405/14 (2006.01)

Patent

CA 2227386

A compound of general formula (A) is described together with pharmaceutically acceptable acid addition salts thereof. The compound a 5-HT1A antagonist which is useful in the treatment of CNS disorders in mammals.

L'invention a pour objet un composé de formule générale (A) ainsi que des sels d'addition d'acide de ce composé, qui sont acceptables sur le plan pharmacologique. Ledit composé est un antagoniste 5-HT1A utile dans le traitement de troubles du système nerveux central chez les mammifères.

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