Novel prostaglandin synthase inhibitors

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 317/00 (2006.01) A61K 31/10 (2006.01) A61K 31/135 (2006.01) A61K 31/16 (2006.01) A61K 31/21 (2006.01) A61K 31/33 (2006.01) C07C 311/15 (2006.01) C07C 311/16 (2006.01) C07C 317/14 (2006.01) C07C 317/22 (2006.01) C07C 317/24 (2006.01) C07C 317/36 (2006.01) C07C 323/65 (2006.01) C07D 207/33 (2006.01) C07D 207/333 (2006.01) C07D 213/52 (2006.01) C07D 213/70 (2006.01) C07D 215/12 (2006.01) C07D 215/14 (2006.01) C07D 217/16 (2006.01) C07D 237/08 (2006.01) C07D 261/08 (2006.01) C07D 263/32 (2006.01) C07D 263/

Patent

CA 2200707

This invention relates to ortho substituted phenyl compounds as inhibitors of prostaglandin synthase, to pharmaceutical compositions comprising such compounds and to methods of using such compounds as antiinflammatory and antipyretic agents. The class of compounds useful in this method of treatment is represented by formula (I).

L'invention porte sur des composés phényliques orthosubstitués inhibiteurs de la prostaglandine-synthase, sur des préparations pharmaceutiques contenant lesdits composés et sur leur mode d'utilisation comme agents anti-inflammatoires et antipyrétiques. La catégorie des composés utilisés dans cette méthode de traitement est représentée par la formule (I).

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