Injection-molded dosage form

Details Injection-molded dosage form Injection-molded dosage form

C - Chemistry, Metallurgy

08

L

C08L 67/04 (2006.01) A61K 9/00 (2006.01) A61K 9/20 (2006.01) A61K 9/32 (2006.01) A61K 47/34 (2006.01) A61K 47/38 (2006.01) B01D 71/48 (2006.01) C08L 1/28 (2006.01) C08L 71/02 (2006.01)

Patent

CA 2200746

The present application discloses a dosage form for delivering a therapeutic agent to an environment of use, the dosage form comprising: (a) an internal compartment; (b) a therapeutic composition comprising a therapeutic agent in the compartment; (c) an expandable composition comprising means for expanding for pushing the therapeutic composition from the dosage form in the compartment; (d) exit means in the dosage form that connects the therapeutic composition with the environment of use, and wherein the dosage form is characterized by: (e) an injection-molded membrane with a softening point below 200°C, permeable to the passage of fluid that surrounds and defines the internal compartment, the injection-molded membrane comprising (i) polycaprolactone or a polycaprolactone copolymer; and (ii) one or more members selected from poly(alkylene oxide) and poly(ethylene glycol).

L'invention concerne une forme galénique comprenant un élément d'enveloppe moulé par injection, exempt de solvants organiques.

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