Use of 4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine...

Details Use of 4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine... Use of 4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine...

A - Human Necessities

61

K

167/251, 167/273

A61K 31/135 (2006.01) A61K 31/275 (2006.01)

Patent

CA 2011428

64680-535 P.C. 7556 USE OF 4-PHENYL-1,2,3,4-TETRAHYDRO-1-NAPHTHALENAMINE DERIVATIVES IN THE TREATMENT OF PSYCHOSIS, INFLAMMATION AND AS IMMUNOSUPPRESSANTS Abstract 4-Phenyl-1,2,3,4-tetrahydro-1-napthalenamine derivatives have been found useful for the treatment of pyschosis, inflammation and as immunosuppressants. Image wherein R1 is selected from the group consisting of hydro- gen and C1-C3 alkyl; R2 is C1-C3 alkyl; Z is Image [wherein X and Y are independently selected from the group consisting of hydrogen, fluoro, chloro, bromo, trifluoromethyl, C1-C3 alkoxy and cyano, with at least one of X and Y other than hydrogen]; and W is selected from the group consisting of hydrogen, fluoro, chloro, bromo, trifluoromethyl and C1-C3 alkoxy or a pharmaceutically acceptable acid addition salt there- of.

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