Method for preparing a marked purine derivative, said...

C - Chemistry – Metallurgy – 07 – D

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C07D 473/04 (2006.01) A61K 51/00 (2006.01) C07B 59/00 (2006.01)

Patent

CA 2710900

The invention relates to a method for preparing a 2-fluoro-purine derivative marked with the 18F radioisotope that comprises the step of fluorinating a 2-nitro-purine derivative. The invention also relates to a 2-fluoro-purine derivative marked with the 18F radioisotope that can be obtained by or during a method according to the invention, and to the different uses thereof.

La présente invention concerne un procédé de préparation d'un dérivé de 2- fluoro-purine marqué avec le radioisotope 18F comprenant une étape de fluoration d'un dérivé de 2-nitro- purine. La présente invention comprend un dérivé de 2--fluoro-purine marqué avec le radioisotope 18F susceptible d'être obtenu par ou au cours d'un procédé selon l'invention et ses différentes utilisations.

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