An improved process to prepare treprostinil, the active...

C - Chemistry – Metallurgy – 07 – C

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C07C 51/08 (2006.01) C07C 51/41 (2006.01) C07C 59/62 (2006.01) C07C 405/00 (2006.01)

Patent

CA 2710205

This present invention relates to an improved process to prepare prostacyclin derivatives. One embodiment provides for an improved process to convert benzindene triol to treprostinil via salts of treprostinil and to purify treprostinil.

La présente invention concerne un procédé amélioré de préparation de dérivés de prostacycline. Un mode de réalisation se rapporte à un procédé amélioré pour convertir du benzindène triol en tréprostinil par le biais de sels de tréprostinil et pour purifier le tréprostinil.

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